In a short-term, clinical trial with ABILIFY MAINTENA in patients with schizophrenia treated with gluteal administered ABILIFY MAINTENA, the percent of patients reporting any injection site-related adverse reaction was 5.4%, and 0.6% for placebo. Important Warning and Precaution Regarding Injection Site Reactions Each box of ABILIFY MAINTENA offers needle options for deltoid and gluteal administration-no additional ordering needed.Rotate site of injection between the 2 deltoid or gluteal muscles.Needle options are conveniently color-coded based on the size of patient and site of administration
All doses can be given by deltoid or gluteal intramuscular administration 400 mg and 300 mg doses may be given via the deltoid and gluteal injection sites Dosage adjustments are not recommended for patients with concomitant use of CYP3A4 inhibitors, CYP2D6 inhibitors or CYP3A4 inducers for less than 14 days. Avoid concomitant use of CYP3A4 inducers with ABILIFY MAINTENA for greater than 14 days. Important Warning and Precaution Regarding Concomitant MedicationÄosage adjustments are recommended in patients who are CYP2D6 poor metabolizers and in patients taking concomitant CYP3A4 inhibitors or CYP2D6 inhibitors for greater than 14 days.
Abilify medication full#
For additional dosage and administration information, please see FULL PRESCRIBING INFORMATION, including BOXED WARNING.If there are adverse reactions with the 400 mg dosage, consider reducing the dosage to 300 mg.After the first injection of ABILIFY MAINTENA, treatment with oral aripiprazole ( 10 mg to 20 mg) or current oral antipsychotic should be continued for 14 consecutive days.ABILIFY MAINTENA is to be administered by either deep intramuscular deltoid or gluteal injection by a healthcare professional.*Oral aripiprazole ( 10 mg to 20 mg) or current oral antipsychotic. For patients already stable on oral aripiprazole or another oral antipsychotic, after the first ABILIFY MAINTENA injection, continue treatment with the antipsychotic for 14 consecutive days.For patients without a history of aripiprazole use, establish tolerability for up to 2 weeks with oral aripiprazole prior to initiating therapy.Initiation and Dosing ABILIFY MAINTENA is a once-monthly LAI you can initiate from any oral antipsychotic Recommended starting and maintenance dose of ABILIFY MAINTENA is 400 mg once monthly 1